Mission Espiritu Santo de Zuniga was originally established in 1722 on the site of LaSalle's Ft. St Louis, near the present Port Lavaca. In 1749, the mission, and the associated presidio, were moved to their present locations, near Goliad, some 40 miles.
Structures included the church, granary, living quarters and outer walls. These were composed of large dressed stone blocks, the only such stuctures among the Texas missions. The mission was closed in 1830 by the Mexican government, and building materials were taken from the mission for use in local residences.
Reconstruction on the original foundations was done by the Civilian Conservation Corps, based on archeological and historical research. The structures are now owned and managed by the Texas Parks and Wildlife Department.